diff --git a/tools/run_on_app.py b/tools/run_on_app.py
index bdb1df8..bab9b32 100755
--- a/tools/run_on_app.py
+++ b/tools/run_on_app.py
@@ -119,6 +119,7 @@
 # do Bug: #BUG in the commit message of disabling to ensure re-enabling
 DISABLED_PERMUTATIONS = [
     ('youtube', '12.10', 'dex'), # b/116089492
+    ('youtube', '12.10', 'proguarded'), # b/116089492
     ('gmscore', 'latest', 'deploy') # b/116575775
 ]