diff --git a/src/test/java/com/android/tools/r8/shaking/addconfigurationdebugging/ConfigurationDebuggingWithInliningTest.java b/src/test/java/com/android/tools/r8/shaking/addconfigurationdebugging/ConfigurationDebuggingWithInliningTest.java
new file mode 100644
index 0000000..6256a35
--- /dev/null
+++ b/src/test/java/com/android/tools/r8/shaking/addconfigurationdebugging/ConfigurationDebuggingWithInliningTest.java
@@ -0,0 +1,81 @@
+// Copyright (c) 2023, the R8 project authors. Please see the AUTHORS file
+// for details. All rights reserved. Use of this source code is governed by a
+// BSD-style license that can be found in the LICENSE file.
+
+package com.android.tools.r8.shaking.addconfigurationdebugging;
+
+import static org.hamcrest.CoreMatchers.containsString;
+import static org.junit.Assert.assertThrows;
+
+import com.android.tools.r8.CompilationFailedException;
+import com.android.tools.r8.NeverInline;
+import com.android.tools.r8.TestBase;
+import com.android.tools.r8.TestParameters;
+import com.android.tools.r8.TestParametersCollection;
+import org.junit.Test;
+import org.junit.runner.RunWith;
+import org.junit.runners.Parameterized;
+import org.junit.runners.Parameterized.Parameter;
+import org.junit.runners.Parameterized.Parameters;
+
+/** This is a reproduction of b/298965633. */
+@RunWith(Parameterized.class)
+public class ConfigurationDebuggingWithInliningTest extends TestBase {
+
+  @Parameter() public TestParameters parameters;
+
+  @Parameters(name = "{0}")
+  public static TestParametersCollection data() {
+    return getTestParameters().withAllRuntimesAndApiLevels().build();
+  }
+
+  @Test
+  public void testForR8() throws Exception {
+    assertThrows(
+        CompilationFailedException.class,
+        () ->
+            testForR8(parameters.getBackend())
+                .addProgramClasses(Main.class, Bar.class)
+                .addKeepRules("-addconfigurationdebugging")
+                .addKeepMainRule(Main.class)
+                .setMinApi(parameters)
+                .enableInliningAnnotations()
+                // TODO(b/298965633): We should not fail.
+                .compileWithExpectedDiagnostics(
+                    diagnostics ->
+                        diagnostics.assertErrorMessageThatMatches(
+                            containsString("Cannot compute relationship for not set"))));
+  }
+
+  public static class Main {
+
+    public static void main(String[] args) throws Exception {
+      System.out.println("Hello World");
+      callM();
+    }
+
+    private static String getObjectName() {
+      return new StringBuilder()
+          .append("com.android.tools.r8.shaking.addconfigurationdebugging")
+          .append(".ConfigurationDebuggingWithInliningTest$Bar")
+          .toString();
+    }
+
+    @NeverInline
+    private static void callM() {
+      try {
+        Bar bar = (Bar) Class.forName(getObjectName()).newInstance();
+        bar.print();
+      } catch (Exception e) {
+        throw new RuntimeException(e);
+      }
+    }
+  }
+
+  public static class Bar {
+
+    public void print() {
+      System.out.println("Initialized");
+    }
+  }
+}