diff --git a/src/main/java/com/android/tools/r8/utils/InternalOptions.java b/src/main/java/com/android/tools/r8/utils/InternalOptions.java
index 40633b6..a5f672e 100644
--- a/src/main/java/com/android/tools/r8/utils/InternalOptions.java
+++ b/src/main/java/com/android/tools/r8/utils/InternalOptions.java
@@ -205,7 +205,8 @@
       !Version.isDevelopmentVersion()
           || System.getProperty("com.android.tools.r8.disableinlining") == null;
   // TODO(b/141451716): Evaluate the effect of allowing inlining in the inlinee.
-  public boolean applyInliningToInlinee = false;
+  public boolean applyInliningToInlinee =
+      System.getProperty("com.android.tools.r8.applyInliningToInlinee") != null;
   public int applyInliningToInlineeMaxDepth = 0;
   public boolean enableInliningOfInvokesWithNullableReceivers = true;
   public boolean disableInliningOfLibraryMethodOverrides = true;
diff --git a/tools/run_on_app.py b/tools/run_on_app.py
index 0941623..c31bfea 100755
--- a/tools/run_on_app.py
+++ b/tools/run_on_app.py
@@ -509,6 +509,7 @@
     if 'allow-type-errors' in values:
       extra_args.append('-Dcom.android.tools.r8.allowTypeErrors=1')
     if 'proto-shrinking' in values:
+      extra_args.append('-Dcom.android.tools.r8.applyInliningToInlinee=1')
       extra_args.append('-Dcom.android.tools.r8.fieldBitAccessAnalysis=1')
       extra_args.append('-Dcom.android.tools.r8.generatedExtensionRegistryShrinking=1')
       extra_args.append('-Dcom.android.tools.r8.generatedMessageLiteShrinking=1')